For dogs suffering from or at risk from mixed parasitic infections : For the treatment and prevention of flea infestation (Ctenocephalides felis) treatment of biting lice (Trichodectes canis) treatment of ear mit infestation (Otodectes cynotis) sarcoptic mange (caused by sarcoptes scabiei var. canys) demodicosis ( caused by demodex canis) prevention of heartworm disease (L3 and L4 larvae of dirofilaria immitis) treatment of angiostrongylus vasorum adn treatment of infections with gastrointestinal nematodes (L4 larve immature adults and adults of toxocara canis ancylostoma caninum and uncinaria stenocephala adults of toxascaris leonina and trichuris vulpis). The product can be used as part of a treatment strategy for flea allergy dermatitis (FAD).• The treatment of circulating microfilariae (Dirofilaria immitis).• The prevention of cutaneous dirofilariosis (L3 larvae of Dirofilaria repens).• The reduction of circulating microfilariae (Dirofilaria repens).• The prevention of spirocercosis (Spirocerca lupi).