Hormone replacement therapy (HRT) for estrogen deficiency symptoms in menopausal women at least 6 months since last menses.Prevention of osteoporosis in postmenopausal women at high risk of future fractures. Femoston 1/10 should only be used in patients who are intolerant of other products, approved for the prevention of osteoporosis or for whom these products are contra-indicated.Femoston is indicated for women with an intact uterus.Experience with treatment of women older than 65 years is limited.