Esoprim S.K. 20 mg indicated in adults for:Gastroesophageal Reflux Disease (GERD)- treatment of erosive reflux esophagitis - long-term management of patients with healed esophagitis to prevent relapse - symptomatic treatment of gastroesophageal reflux disease. In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori and- healing of Helicobacter pylori associated duodenal ulcer and prevention of relapse of peptic ulcers in patients with Helicobacter pylori associated ulcers -Patients requiring continued NSAID therapy Healing of gastric ulcers associated with NSAID therapy. - Prevention of gastric and duodenal ulcers associated with NSAID therapy, in patients at risk. - Prolonged treatment after i.v. induced prevention of rebleeding of peptic ulcers. Esoprim S.K 20 mg is indicated in adolescents from the age of 12 years for: Gastro-esophageal Reflux Disease (GERD) - treatment of erosive reflux esophagitis -long-term management of patients with healed esophagitis to prevent relapse-symptomatic treatment of gastro-esophageal reflux diseaseIn combination with antibiotics in treatment of duodenal ulcer caused by Helicobacter pylori.