Vinblastine has proved effective in the treatment of the following neoplasms, either alone or in conjunction with other oncolytic drugs:Frequently Responsive Malignancies :• Generalized Hodgkin's disease (Stages III and IV, Ann Arbor modification of Rye staging system)• Non-Hodgkin's lymphoma: - Reticulum-cell sarcoma - Lymphosarcoma• Mycosis fungoides.• Neuroblastoma.• Histiocytosis X.Less Frequently Responsive Malignancies :• Choriocarcinoma resistant to other chemotherapeutic agents.• Embryonal carcinoma of the testis.• Carcinoma of the breast, unresponsive to appropriate endocrine surgery and hormonal therapy.