Prophylaxis of organ rejection in kidney, liver, heart allogenic transplants in conjunction with corticosteroids. May also be used in the treatment of chronic rejections in patients previously treated with other immunosuppresive agents. Bone marrow transplantation. Endogenous uveitis. Severe psoriasis above age 16 that does not respond to other treatment . Atopic dermatitis in adults only up to 8 weeks, for severe cases in which conventional therapy is ineffective or inappropriate. Rheumatoid arthritis, severe cases when standard treatment is ineffective or inappropriate. Nephrotic syndrome type MCD (minimal change disease) in cases where conventional therapy has failed.