Varicella zoster virus (VZV) infections – herpes zoster:Valtrex is indicated for the treatment of herpes zoster (shingles) and ophthalmic zoster in immunocompetent adults.Valtrex is indicated for the treatment of herpes zoster in adult patients with mild or moderate immunosuppression.Herpes simplex virus (HSV) infections:Valtrex is indicated for the treatment and suppression of HSV infections of the skin and mucous membranes including- treatment of first-episode of genital herpes in immunocompetent adults and adolescents and in immunocompromised adults- treatment of recurrences of genital herpes in immunocompetent adults and adolescents, and in immunocompromised adults- suppression of recurrent genital herpes in immunocompetent adults and adolescents and in immunocompromised adultsTreatment and suppression of recurrent ocular HSV infections in immunocompetent adults and adolescents and in immunocompromised adults Clinical studies have not been conducted in HSV-infected patients immunocompromised for other causes than HIV-infection.Cytomegalovirus (CMV) infections:Valtrex is indicated for the prophylaxis of CMV infection and disease following solid organ transplantation in adults and adolescents