* Cattle: Therapeutic and preventive treatment (metaphylaxis) of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni.The presence of the disease in the herd should be established before preventive treatment. * Pigs (Swine): Treatment of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida and Haemophilus parasuis. * Sheep:Treatment of infectious pododermatitis (foot rot) associated with virulent Dichelobacter nodosus and Fusobacterium necrophorum requiring systemic treatment.