Treatment of resistant schizophrenic patients who are non-responsive to, or intolerant of classic neuroleptics.Reducing the risk of recurrent suicidal behavior in patients with schizophrenia or schizoaffective disorder who are judged to be at chronic risk for re-experiencing suicidal behavior, based on history and recent clinical state.Suicidal behavior refers to actions by a patient that put him/herself at risk for death