Mannitol 20%, Solution for Infusion is indicated for: - The promotion of diuresis, in the prevention and/or treatment of the oliguric phase of acute renal failure before irreversible renal failure becomes established; - The reduction of intracranial pressure and treatment of cerebral edema by reducing brain mass; - The reduction of elevated intraocular pressure when the pressure cannot be lowered by other means, and promoting the urinary excretion of toxic substances