Benzodiazepine antagonist for reversal of benzodiazepine anesthesia, as well as for patients with Benzodiazepine intoxication. In a hospital setting:In anaesthesiology to neutralise the sedative effects of benzodiazepines on the central nervous system in adults and children older than 1 year:• reversal of sedative effect during general anaesthesia induced and maintained by benzodiazepines,• reversal of conscious sedation induced by benzodiazepines in short operations with a diagnostic or therapeutic objective.In intensive care to neutralise the sedative effects of benzodiazepines on the central nervous system and treat a coma of unknown aetiology, in adults and children (including newborns) if the semiology is compatible with the hypothesis of a benzodiazepine or related substance-induced coma:• diagnosis and/or treatment of intentional or accidental benzodiazepine overdose,• aetiological diagnosis of an unexplained coma in order to differentiate what is caused by a benzodiazepine from another cause (pharmacological or neurological).• specific cancellation of the effects on the central nervous system by excessive benzodiazepine doses (re-establishment of spontaneous ventilation to avoid intubation or interrupt ventilatory assistance).In an emergency situation or medical transport, in adults and children older than 6 years:• reversal of benzodiazepine-induced conscious sedation in case of respiratory depression or apnoea.